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Normoxic Polymer Gel of Hydroxy-Ethyl-Acrylate (HEA) as Radiation Therapy Dosimeter

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Dr. Mohamed Omer Mohamed Mohamed Yousef,M. E. M. Gar elnabi ,E. . Saion ,E. A. A. Balla ,A. A. Al-Zahrany ,Y. M. Yousif ,M. H. Haron ,Kh. M. Dahlan ,2011, Normoxic Polymer Gel of Hydroxy-Ethyl-Acrylate (HEA) as Radiation Therapy Dosimeter,Journal of Science and Technology,12 (1) ,pp:45-50

Authors:
By Dr. Mohamed Omer Mohamed Mohamed Yousef,M. E. M. Gar elnabi ,E. . Saion ,E. A. A. Balla ,A. A. Al-Zahrany ,Y. M. Yousif ,M. H. Haron ,Kh. M. Dahlan ,
Year:
2011
Keywords
Polymer Dosimeter in Radiotherapy,HEA .
Abstract
An absorbed X-radiation dose in the range of radiotherapy for cancer patients (0-12 Gy) was measured and characterized in a polymer/Gel dosimeter (Polym/Gel) which composed of normoxic hydroxyl-ethyl-acrylate/Gel (HEA/Gel). The characterization of the irradiated HEA/Gel by Nuclear Magnetic Resonance (NMR) showed that the relaxation rate R2 (t) for proton was increased following the radiation dose indicating the polymerization of HEA/Gel monomer to poly(hydroxylethyl- acrylate/Gel) PHEA/Gel. The PHEA/Gel was characterized by Raman spectroscopy which confirmsed the polymerization of HEA/Gel with reference to the a new chemical bond formation at Raman shift of 1415 cm-1which in turn was being increased following the radiation dose. The color change of PHEA/Gel due to radiation polymerization was been studied by optical density-meter out of MRI image which showed that the optical density increased along the axis of the radiation field in depth profile for a limited distance then decreased by increasing the radiation.
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