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Profile of Antibiotic Sensitivity and Resistance of Some Pathogenic Bacteria Isolated from Clinical Specimens in Sudan

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Prof. Humodi Ahmed Saeed Nasser,2011, Profile of Antibiotic Sensitivity and Resistance of Some Pathogenic Bacteria Isolated from Clinical Specimens in Sudan,Journal of Science and Technology,12 (1) ,pp:14-19

Authors:
By Prof. Humodi Ahmed Saeed Nasser,
Year:
2011
Keywords
Antibiotic sensitivity and resistance, Pathogenic bacteria.
Abstract
In this study the activity of gentamicin, ciprofloxacin, ceftazidinime impenem, amikacin, tetracycline, penicillin, nalidixic acid and nitrofurantoin was evaluated. A total of 380 clinical specimens were collected from different hospitals in Khartoum state. Different types of bacteria were isolated. These include Staphylococcus aureus (n=37), Escherichia coli (n=70), Klebsiella pneumoniae (n=15), Proteus spp. (n=57) and Pseudomonas aeruginosa (n=67).The study revealed that the profile of antibiotics sensitivity and resistance were as follows: Gentamicin 90.8 and 9.2%, ciprofloxacin 72.1 and 27.9%, ceftazidinime 100.0 and 0.0%, impenem 100.0 and 0.0%, amikacin 94.0 and 6.0%, tetracycline 47.7 and 52.3%, nalidixic acid 65.9 and 34.1% and nitrofurantoin 86.3 and 13.7%, penicillin 16.7 and 83.3% and erythromycin 75.9 and 24.1% respectively. The study concluded that ceftazidinime and impenem were the most effective antibiotics against Pseudomonas aeruginosa isolated from wounds.
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